The following is an extract taken from our forthcoming book titled The Real Truth about SPICE.
Spice is synthetic cannabis.
Please read our blog presenting the real truth about Cannabis, also known as Marijuana – https://simplelivingglobal.com/the-raw-truth-about-marijuana/
K2 is the name given to Spice in the U.S.
Many of us may know of the drug called Spice but have no idea really what it actually is and what it does to the human frame.
SPICE IS NOT DESIGNED FOR HUMAN CONSUMPTION.
It is a man-made drug that alters our natural state and creates extreme behaviour that we have not seen or felt before. In other words, we have taken this to another level.
Is it time to look at WHY anyone would want to take this intense drug?
Is it time we addressed our global drug epidemic, which is out of control?
Are we seriously considering the knock on effect of what this drug is doing?
Are we busy blaming or are we trying to find solutions, which are band-aids?
Are we ready to read what is being presented in this article and take note of the dangers of this harmfull substance?
Are we going to wake up and realise that our world is in deep trouble if some people are choosing to take this lethal drug?
Are we going to wait for more and more research to confirm what common sense is telling us right now?
Are we ever going to fund research to get to the root cause of WHY anyone chooses to take drugs in the first place, to alter their natural state of being?
What is Spice?
Spice is not a single drug but a range of laboratory-made chemicals that mimic the effects of THC – tetrahydrocannabinol which is the main psychoactive component of cannabis. Research suggests that Spice and other forms of synthetic cannabis is capable of producing much more intense and prolonged effects at much lower doses than natural cannabis.
This is because cannabis in its natural form reacts partially with the body and synthetic cannabis reacts far more fully.
To understand the biology behind the intense reaction to Spice, we need to look at the parts of the body’s central nervous system that react to cannabis – the cannabinoid receptors and the chemical part of the drug that reacts with the body – the “agonist”.
While THC is a “partial agonist” (it only partially reacts with cannabinoid receptors), synthetic cannabis is often a “full agonist”. In this way, the more adverse effects observed with synthetic cannabis use stem from its ability to completely saturate and activate all of the body’s cannabinoid receptors at a lower dose.
Although the consequences of long-term regular use are not well defined, experts believe that synthetic cannabis has the potential to develop, or cause a relapse of mental illness. (1)
Long-term side effects range from nausea and tooth loss to heart and lung problems. (2)
WHY would anyone want to make a drug in a laboratory that mimics the effects of cannabis?
WHO on earth comes up with stuff that is more potent and harmfull to the mind and body?
Do we need experts to tell us or can we work it out, that synthetic cannabis is going to cause some form of mental illness because of the very nature of what it is?
For those who are choosing this drug, are they even bothered about the long-term side effects?
Where does Spice come from?
In late 1980’s scientists discovered that THC in cannabis affects humans by stimulating those receptors in the brain and nervous system that process sensation, appetite, mood and memory.
Once this had been established, chemists researching new medicines were able to synthesise compounds specifically to target these receptors and went on to create them in their hundreds.
Just as drugs such as MDMA (ecstasy) had before these, gradually seeped out of the lab and onto the street. (3)
First synthetic cannabinoid identified on the recreational drug market. (1)
Spice was the first well-known brand name. (3)
Synthetic cannabinoids laced on plant material were first reported in the U.S. when a shipment of “Spice” was seized and analysed by U.S. Customs and Border Protection (CBP) in Ohio. (4)
Scientific and law enforcement communities started studying what was actually contained in synthetic cannabis mixtures.
Analysis showed the product had been sprayed with synthetic cannabinoids. It was not a simple mixture of harmless herbs such as canavalia, maritime, leonotis, zornia and others.
These are NOT the “All Natural” ingredients listed on packaging and sellers’ websites.
These chemicals are similar to natural cannabinoid found in marijuana –
THC – tetrahydracannabinol but they affect our brain receptors differently.
Spice and K2 may contain one of many synthetic cannabinoids such as
Phenazapam prescription drug has also been found in some products.
Synthetic cannabinoids fit into the same receptors as THC latches onto in the brain, so they can have an effect similar to THC.
Note – some synthetic cannabinoids are 100 X stronger than THC and many operate on other brain receptors too. (5)
JWH-018 an aminoalkylindole (AAIs) originally developed by a researcher in a US university was sold under the brand name Spice.
AAIs are the most common sub-family of synthetic cannabinoids and are produced in kilogram quantities through quick and simple chemical reactions using legal substances. (1)
Synthetic cannabinoids are included in a group of drugs called “new psychoactive substances” (NPS). (6)
Under narcotics legislation, JWH-018 is now a controlled substance in many countries.
The prevalence of next-generation synthetic cannabinoids, known as Spice or Mamba continue to be the largest group of New Psychoactive Substances (NPS) in common usage. (1)
The chemistry to make these things is very simple and very old.
You only have three easily available starting materials and only two steps.
In a few days, you could make 25g, which could be enough to make havoc.
These substances are produced on a large scale by chemical companies based in China then shipped as bulk powders to Europe by air or sea.
Once in Europe, the synthetic cannabinoids are mixed with plant material using solvents like acetone or methanol to dissolve the powders.
The combination is then dried, packaged and sold as either incense or smoking mixtures. (1)
By the end of 2015, 14 different sub-families of cannabinoid agonists have been identified, indicating that there are potentially hundreds of these types of substances circulating via the Internet and often across international borders. (1)
51 new synthetic cannabinoids were identified in 2012, compared to just 2 in 2009. (4)
The wide range of cannabinoids available have for years made such drugs very difficult for legislators to tackle.
Manufactures simply tweaked the formula, to produce substances with a chemical make-up slightly altered from the most recently banned version. (3)
Although it is usually sold as a herb resembling marijuana, this is a marketing gimmick. (3)
Would it be true to say we are very good at creating the supply if we know there is a demand?
Are the chemical companies even considering what they are producing and where it will end up?
Are those receiving the bulk shipments in Europe deliberately creating a product that they know has a mass demand?
Do manufacturers think they are clever because they can tweak formulas and stay one step ahead of the current legislation?
WHY is there not a public outcry to ban ALL ranges of cannabinoids?
Is this simply about profit before people?
Or is there more here that needs to be addressed?
Would it be true to say that those who have a direct hand in this process are not living a life of integrity?
Would it be true to say that all those involved are not choosing to live with the word RESPONSIBILITY?
What are Synthetic Cannabinoids?
Mind altering chemicals that are –
- Inhaled as cigarettes
- Liquid incense
- Liquids to be vaporised
- Shredded plant material so they can be smoked – herbal incense
These chemicals are called cannabinoids because they are related to chemicals found in the marijuana plant.
Due to the similarity, synthetic cannabinoids are sometimes misleadingly called “fake weed” and they are often marketed as “safe” legal alternatives to that drug.
In fact, they may affect the brain much more powerfully than marijuana; their actual effects can be unpredictable and in some cases, severe or even life-threatening. (6)
Manufacturers sell these herbal incense products in colourful foil packages and sell similar liquid incense products like other e-cigarette fluids, in plastic bottles.
These products are marketed under a wide variety of specific brand names; in the past years
K2 and Spice were common.
There are now hundreds of brand names such as Joker, Black Mamba and Kronic.
For several years, synthetic cannabinoid mixtures were easy to buy in drug paraphernalia shops, novelty stores, gas stations and through the Internet.
The chemicals used have a high potential for abuse and no medical benefit.
Authorities in USA have made it illegal to buy, sell or possess some of these chemicals.
However, manufacturers try to sidestep these laws by changing the chemical formulas in their mixtures. (6)
Easy access and the belief that synthetic cannabinoid products are “natural” and therefore harmless have likely contributed to their use among young people.
Who on earth comes up with names like this?
Who is the Joker here inside our minds playing these games?
WHY would a name of a highly venomous snake be appealing?
WHY are we not getting clues from the names like Kronic?
WHY has this drug become easy access for so many?
What is the Intelligence1 that fools us to believe these synthetic substances are “natural”?
WHY would manufacturers try and side step our laws by changing the formula?
WHY are we not demanding answers to questions like those raised in this article?
Synthetic cannabinoids are often labelled “not for human consumption.”
Labels often claim that they can contain “natural” material taken from a variety of plants.
The only parts of these products that are natural are the dried plants materials.
Chemical tests show the active, mind altering ingredients are cannabinoid compounds made in laboratories. (6)
Standard drug tests cannot easily detect many of the chemicals used in these products. (6)
Synthetic Cannabinoids have No Commercial Uses. (7)
As a world, WHY do we accept False Advertising?
WHY does dodgy selling happen in the first place?
WHY are marketing companies willing to lie to us at any cost?
WHY are labels not telling the truth – why are they hiding?
WHY do we choose to ignore “not for human consumption”?
WHY are our drug testing methods one step behind in detecting?
Spice is NOT Legal.
It is now banned in most Western nations. (3)
Can we join the dots here and keep it simple?
Spice is an illegal substance.
There is a valid reason why it is banned.
Why are we choosing to ignore these simple facts?
Use of Spice in large quantities was first noted by the British authorities a decade ago.
2010 – the main synthetic cannabinoid – JWH-018 was made illegal.
26 May 2016 – the production, distribution, sale and supply of Spice became illegal under the Psychoactive Substances Act 2016. (8)
The above Act was in place in England.
However, the possession of Spice was only illegal for prisoners.
Legal Highs was a term used to describe substances that mimicked the effects of illegal drugs but had been tweaked at a molecular level to avoid previous anti-drug laws. (9)
December 2016 – UK Government classified strains of synthetic cannabinoids, which are commonly referred to as ‘Spice’ as a Class B controlled substance under the Misuse of Drugs Act 1971 (MDA). This means those found to be in possession can face up to 5 years in prison and an unlimited fine. (10)
Spice can still be bought online in Ireland. (11)
DEA Schedule/Legal Status
Schedule 1 drug (7)
Drug Enforcement Administration (DEA) used emergency protocols to temporarily schedule some of the substances found in synthetic cannabinoid products.
President Obama signed the Synthetic Drug Abuse Prevention Act, permanently placing several different classes of psychoactive substances, including many synthetic cannabinoids, into Schedule 1 of the Controlled Substances Act (CSA) – the most restrictive classification. (12)
The U.S. Food and Drug Administration (FDA) have approved three medications containing synthetically derived cannabinoids to treat severe nausea and wasting in certain circumstances.
Development programs of products that contain marijuana or their synthetic equivalents are being fast tracked by the FDA for ‘therapeutic purposes’. (7)
Each state is currently using various administration actions, prosecution strategies and regulations for product labelling and branding to either quickly ban individual substances or criminalize sales.
Most states have also enacted criminal and civil penalties and others have pending legislation for the sale of products that attempt to avoid being advertised as “synthetic drugs” by claiming they are “not for human consumption”. (12)
Synthetic Cannabinoids – second most frequently used illegal drug among high school seniors. (4)
WHY are synthetic cannabinoids so popular with high school seniors?
What on earth is going on for our Youth of today?
WHY do they need mind altering drugs at such a young age?
(1) Ralphs, R., & Sutcliffe, O. (2016, September 23). What is Spice and Why is the Drug So Dangerous? The Conversation. Retrieved October 21, 2017 from
(2) Malone, A. (2017, March 13). Rise of the Zombies: Cheaper and More Addictive than Crack, Spice is the Synthetic Drug that Turns Users into the ‘Living Dead’ in Minutes and is Ruining Lives Across Britain. MailOnline. Retrieved October 21, 2017 from http://www.dailymail.co.uk/news/article-4302806/Spice-synthetic-drug-turns-users-living-dead.html
(3) (2017, March 25). A New and Deadly Spice Trade. The Week. Issue 1117, p.13
(4) (n.d). Synthetic Drugs (a.k.a. K2, Spice, Bath Salts, etc.). Office of National Drug Policy Control. www.obamawhitehouse.archives.gov. Retrieved October 21, 2017 from
(5) (2017, April 8). What Is Spice/K2? The Facts on Synthetic Marijuana 2017. Spice Addiction Support. Retrieved October 21, 2017 from
(6) (2015, November). What Are Synthetic Cannabinoids? National Institute on Drug Abuse. Retrieved October 21, 2017 from
(7) (2016, November). Facing Addiction in America: The Surgeon General’s Report on Alcohol, Drugs, and Health. (pp. 1-22, p. 80). U.S. Department of Health and Human Services (HHS), Office of the Surgeon General. Washington, DC: HHS
(8) (2016, May 26). Legal Highs Ban Comes into Force Across the UK. BBC News. Retrieved October 21, 2017 from
(9) (2017, February 7). Legal Highs: What Are They and Has the Government Ban Worked? The Week. Retrieved October 26, 2017 from
(10) (2017, January 23). Changes to Drugs Legislation re: ‘Spice’. Metropolitan Police. Retrieved October 21, 2017 from
(11) (2016, August 4). Spice Training. Turning Point, London.
(12) (n.d). Are Synthetic Cannabinoids Legal? Drug Policy Alliance. Retrieved October 21, 2017 from